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ViewAttendees 3

10-Minute Paper

Physiology, Biochemistry, and Toxicology

PBT: Cold Physiology and Nucleotides

Sex-specific transcriptional profiles during diapause in the Colorado potato beetle

Sunday, November 5, 2023
10:00 AM – 10:12 AM ET
Location: Gaylord National Resort & Convention Center, National Harbor 11
In-Person
To cope with harsh environmental conditions, many overwintering insects enter diapause. Many of the phenotypic changes that occur during diapause are well understood, but less is known about their underlying physiological mechanisms and how these mechanisms might differ between sexes. Here, we used RNA-seq to compare transcriptomic profiles of adult diapausing and non-diapausing Colorado potato beetle (Leptinotarsa decemlineata) males and females. We observed significant sex-specific gene expression profiles, a global decrease in the expression of genes related to aerobic metabolism, evidence of a G2/M cell-cycle arrest, and differential expression patterns of genes involved in the insulin and FOXO signaling pathways, supporting their central role in diapause regulation.